Our orthobiologic products are designed to help patients return to their active lives more quickly and naturally. At ANSTEM Medical, we are proud to offer a family of Anika viscosupplements to manage pain for all patients - from those with acute sports injuries to patients suffering degenerative osteoarthritis (OA).

The Anika Advantage:

  • Natural non-animal sourced ultra-pure hyaluronan from bacterial fermentation.
  • Trusted brand for nearly 30 years.
  • Excellent safety profile, with over 35 million treatments worldwide.
  • Strong efficacy profile for a portfolio of products providing rapid and long-term relief from the pain of OA.
  • Convenient non-surgical treatment that avoids oral medication side-effects and may delay the need for total knee replacement (TKR) up to 3.6 years.

What is Osteoarthritis?

Osteoarthritis (OA) is the most common type of arthritis, also known as degenerative joint disease, for which there is no cure. It is a common, chronic, progressive musculoskeletal disorder.

In an osteoarthritic joint, the surface layer of cartilage gradually breaks down and wears away. The bones in the joint that are now exposed and rubbing against each other, causing pain, swelling, and loss of motion. Over time, the joint may lose its normal shape. In addition, small deposits of bone, called bone spurs, may grow on the edges of the joint. These can break off and float inside the joint space, causing even more pain and damage.

Causes of Osteoarthritis?



As a person gets older, the body’s ability to heal damaged or lost cartilage decreases.


Joint injury

Younger people can also develop OA due to joint injury.




If there is a family history of OA, the risk for developing the disease increases


Repeated joint stress

Excess weight or overuse of the joint causes stress or increased wear and tear on the joint


Muscle weakness

If the muscles that surround the joint are weak, added stress is placed on the joint.



Joint disorder

If there is a joint malformation or a genetic defect in the joint cartilage.



Areas affected by Osteoarthritis?








Spine, Neck & Lower Back


Hands, Fingers & Thumbs



Symptoms of Osteoarthritis?






Limitation/Loss of Function




Crackling Noises in Joints

Current Treatment options for Osteoarthritis?

For patients who have been diagnosed with osteoarthritis (OA), their physician will determine the best way to treat their condition based on the severity, the pain, and their lifestyle limitations due to OA.

While there is no cure for OA, there are a number of treatment options that can be explored depending on osteoarthritis severity.

  • Lifestyle: weight loss, exercise, protecting your knees from excess stress, physical therapy
  • Analgesics: simple pain relievers, such as acetaminophen
  • NSAIDS (non-steroidal anti-inflammatory drugs), such as ibuprofen or aspirin
  • Steroids, also called corticosteroids
  • Viscosupplements: hyaluronic acid (HA), also called sodium hyaluronate or hyaluronan
  • Opioids: powerful pain relievers, such as morphine
  • Surgery, such as total knee replacement


When conservative approaches to treating pain due to osteoarthritis, such as physical therapy, weight loss, exercise, or pain relievers are no longer effective, alternative non-surgical treatment options may be beneficial, such as steroids or viscosupplements.


Corticosteroid injections have been used for over 45 years for their potent anti-inflammatory effects to reduce pain quickly. While steroids provide rapid pain relief, the effects are typically short lived. In addition, they may cause additional joint damage or even severe joint destruction if given repeatedly over a long period of time.


Viscosupplements have been used globally for more than 25 years to reduce pain associated with osteoarthritis by improving the viscosity and function of the synovial fluid in the joint. While injections of HA alone can provide you with up to six weeks of pain relief, the patient does not typically experience the peak effects until 8 weeks after the final injection.10

Only CINGAL® works by combining a fast-acting steroid with a long lasting viscosupplement to deliver rapid pain relief proven to last through six months.

Benefits of our Orthobiologic Viscosupplements:

  • Proven to be safe and effective
  • Provide increased mobility and enhanced joint protection
  • Long lasting pain relief demonstrated to last at least through six months*
  • Help to delay total knee replacement surgery up to 3 or more years
  • Improve viscoelastic properties of the synovial fluid 
  • Protect the surface of articular cartilage
  • Well established: used for more than 25 years for the treatment of OA pain
  • Steroids work by providing rapid pain relief from the symptoms of osteoarthritis and reducing inflammation.

Contact your health Care practicioner about our pain-relief products

A Powerful New Treatment for the Pain of Osteoarthritis

CINGAL® is a simple, physician-administered injection that delivers fast acting and long-lasting pain relief for osteoarthritis so patients can once again enjoy daily physical activities with reduced pain.

Contact your Physician for more information on this treatment option.

A Single Injection, Lightly Cross-linked High Molecular Weight Hyaluronic Acid

MONOVISC® has been specially formulated as a single injection procedure. Unlike other hyaluronic acid (HA) viscosupplementation treatment regimens that may require up to five injections, MONOVISC only requires a single injection, the benefits of which are listed below:

  • Pain relief for 6 months.
  • Increases mobility.
  • Decreases office visits compared to multi-injection products.
  • Reduces the risk or difficulty associated with multiple injections.

Contact your Physician for more information on this treatment option.

A High Molecular Weight Hyaluronic Acid Injection

Orthovisc (High Molecular Weight Hyaluronan) is an FDA-approved non-drug therapy, also known as hyaluronic acid or viscosupplementation injections. The only injection made from ultra-pure natural hyaluronan, it contains no buffers or
preservatives. In fact, Orthovisc contains the highest concentration of hyaluronan available per injection.

Contact your Physician for more information on this treatment option.

Find out more about our solutions by contacting your Health Care Professional.

For any other queries, please feel free to contact our team at ANSTEM Medical

"Our mission is to innovate and develop accessible solutions for the highest quality care. We are motivated by a deep sense of responsibility to our fellow man and woman in need."
Stephan Strydom