What is Osteoarthritis?
Osteoarthritis (OA) is the most common type of arthritis, also known as degenerative joint disease, for which there is no cure. It is a common, chronic, progressive musculoskeletal disorder.
In an osteoarthritic joint, the surface layer of cartilage gradually breaks down and wears away. The bones in the joint that are now exposed and rubbing against each other, causing pain, swelling, and loss of motion. Over time, the joint may lose its normal shape. In addition, small deposits of bone, called bone spurs, may grow on the edges of the joint. These can break off and float inside the joint space, causing even more pain and damage.
80% of the population over 65 years old has radiographic evidence of OA. Patients suffering from OA often face chronic pain that worsens over time. Most commonly affecting middle-aged and older people, OA can range from very mild to very severe. There are certain factors that can increase a person’s risk for developing osteoarthritis.
Causes of Osteoarthritis?
As a person gets older, the body’s ability to heal damaged or lost cartilage decreases.
Younger people can also develop OA due to joint injury.
If there is a family history of OA, the risk for developing the disease increases
Repeated joint stress
Excess weight or overuse of the joint causes stress or increased wear and tear on the joint
If the muscles that surround the joint are weak, added stress is placed on the joint.
If there is a joint malformation or a genetic defect in the joint cartilage.
Causes of Osteoarthritis?
Symptoms of Osteoarthritis?
Current Treatment options for Osteoarthritis?
For patients who have been diagnosed with osteoarthritis (OA), their physician will determine the best way to treat their condition based on the severity, the pain, and their lifestyle limitations due to OA.
While there is no cure for OA, there are a number of treatment options that can be explored depending on osteoarthritis severity.
- Lifestyle: weight loss, exercise, protecting your knees from excess stress, physical therapy
- Analgesics: simple pain relievers, such as acetaminophen
- NSAIDS (non-steroidal anti-inflammatory drugs), such as ibuprofen or aspirin
- Steroids, also called corticosteroids
- Viscosupplements: hyaluronic acid (HA), also called sodium hyaluronate or hyaluronan
- Opioids: powerful pain relievers, such as morphine
- Surgery, such as total knee replacement
When conservative approaches to treating pain due to osteoarthritis, such as physical therapy, weight loss, exercise, or pain relievers are no longer effective, alternative non-surgical treatment options may be beneficial, such as steroids or viscosupplements.
Corticosteroid injections have been used for over 45 years for their potent anti-inflammatory effects to reduce pain quickly. While steroids provide rapid pain relief, the effects are typically short lived. In addition, they may cause additional joint damage or even severe joint destruction if given repeatedly over a long period of time.
Viscosupplements have been used globally for more than 25 years to reduce pain associated with osteoarthritis by improving the viscosity and function of the synovial fluid in the joint. While injections of HA alone can provide you with up to six weeks of pain relief, the patient does not typically experience the peak effects until 8 weeks after the final injection.10
Only CINGAL® works by combining a fast-acting steroid with a long lasting viscosupplement to deliver rapid pain relief proven to last through six months.
CINGAL® is a unique single-injection treatment proven to safely and effectively treat the pain and certain symptoms associated with osteoarthritis (OA).1 CINGAL combines two well-established treatments in a single injection, providing the benefits of both an approved corticosteroid and a proprietary high concentration cross-linked hyaluronic acid formulation. CINGAL is a simple treatment performed by a health care professional during an in-office visit.
The corticosteroid reduces inflammation in the joint, providing rapid pain relief within days of injection, while the hyaluronic acid component works in parallel to deliver long lasting pain relief proven to last through 6 months.1
Benefits of Viscosupplements:
- Proven to be safe and effective
- Provide increased mobility and enhanced joint protection
- Long lasting pain relief demonstrated to last at least through six months*
- Help to delay total knee replacement surgery up to 3 or more years
- Improve viscoelastic properties of the synovial fluid
- Protect the surface of articular cartilage
- Well established: used for more than 25 years for the treatment of OA pain
Steroids work by providing rapid pain relief from the symptoms of osteoarthritis and reducing inflammation.
ORTHOVISC-T is an ultra-pure, high molecular weight injectable hyaluronic acid (HA) viscosupplement designed to relieve pain and restore function to tendons damaged by chronic tennis elbow. ORTHOVISC-T provides lubrication to promote tendon gliding, creating a beneficial healing environment.
ORTHOVISC-T is provided in a single-use syringe, and is injected around the affected osteotendinous junction once a week for a total of two injections.
The Orthovisc Advantage:
- Provides pain relief
- Restores physical function
- Improves tendon healing environment
- Allows patients to return to sports they had given up due to pain
- Natural, non-animal sourced HA
MONOVISC is a single injection viscosupplement utilized to treat the joint pain caused by osteoarthritis. It is comprised of highly purified, partially cross-linked sodium hyaluronate (NaHA) in a phosphate buffered saline solution, and it is both biocompatible and resorbable.
With just one injection, MONOVISC may provide pain relief that lasts for up to 6 months.1
MONOVISC is the only non-animal sourced hyaluronic acid (HA) single injection treatment approved for use in the United States, and it delivers the maximum dose of HA (88mg) currently available in any single injection treatment.
The Monovisc Advantage:
- Convenient single injection treatment
- Highly concentrated, non-animal sourced HA
- Long lasting relief through 26 weeks
- Better patient compliance with a single injection than a multi injection product
- No confirmed pseudoseptic reactions reported